Keratinization and Tumor Promotion
نویسندگان
چکیده
منابع مشابه
Keratinization and its disorders.
Keratins are a diverse group of structural proteins that form the intermediate filament network responsible for maintaining the structural integrity of keratinocytes. In humans, there are around 30 keratin families divided into two groups, namely, acidic and basic keratins, which are arranged in pairs. They are expressed in a highly specific pattern related to the epithelial type and stage of c...
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Numerous papillomas and two malignant tumors were elicited in 101 strain mice treated once weekly with applications of acetone extracts of latices of ten species of Euphorbia after a single dose of DMBA in acetone. Of the species tested E. ti~ucalli was the most potent. Three papillomas were seen in 40 mice treated with DMBA only and three among 100 mice treated with latices only. These results...
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An initiation/promotion bioassay for chemical carcinogens and tumor promoters has been developed in rat liver using presumed preneoplastic lesions, foci of gamma-glutamyltranspeptidase (GGTase)-positive hepatocytes, as the endpoint. To evaluate the tumor-promoting activity of phenobarbital, rats were administered diethylnitrosamine (DENA), 2.0 mmole/kg, followed by 500 ppm phenobarbital in thei...
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ژورنال
عنوان ژورنال: Journal of the American College of Toxicology
سال: 1989
ISSN: 0730-0913
DOI: 10.3109/10915818909019548